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Comparison of Prasugrel and Ticagrelor Loading Doses in ST-Segment Elevation Myocardial Infarction Patients RAPID (Rapid Activity of Platelet Inhibitor Drugs) Primary PCI Study

Objectives

This study sought to compare the action of prasugrel and ticagrelor in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PPCI). Background

It has been documented that prasugrel and ticagrelor are able to provide effective platelet inhibition 2 h after a loading dose (LD). However,the pharmacodynamic measurements after prasugrel [...]

Intracoronary Compared With Intravenous Bolus Abciximab Application During Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction Cardiac Magnetic Resonance Substudy of the AIDA STEMI Trial

Objectives

The aim of the AIDA STEMI (Abciximab i.v. Versus i.c. in ST-elevation Myocardial Infarction) cardiac magnetic resonance (CMR) substudy was to investigate potential benefits of intracoronary versus intravenous abciximab bolus administration on infarct size and reperfusion injury in ST-segment elevation myocardial infarction. Background

The AIDA STEMI trial randomized 2,065 patients to intracoronary or [...]

Abciximab During Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction Intracoronary,Intravenous,or Not at All? ⁎ ⁎

The intravenous (IV) route is the standard way to administer abciximab to patients during percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI),but pharmacokinetic principles predict that the intracoronary (IC) route would be better. Because of the short half-life of abciximab and its avid binding to multiple integrin types during the first pass [...]

Fibrinolysis or Primary PCI in ST-Segment Elevation Myocardial Infarction

Most Viewed:NEJM Most Viewed Articles –Week

Effects of Radial Versus Femoral Artery Access in Patients With Acute Coronary Syndromes With or Without ST-Segment Elevation

Objectives

The purpose of this study was to determine the consistency of the effects of radial artery access in patients with ST-segment elevation myocardial infarction (STEMI) and in those with non–ST-segment elevation acute coronary syndrome (NSTEACS). Background

The safety associated with radial access may translate into mortality benefit in higher-risk patients,such as those [...]

Age and Gender Differences in Quality of Care and Outcomes for Patients with ST-segment Elevation Myocardial Infarction

Abstract:Background:Young patients (aged≤45 years) presenting with ST-segment elevation myocardial infarction present unique challenges. The quality of care and in-hospital outcomes may differ from their older counterparts.

Methods:A total of 31,544 patients presenting with ST-segment elevation myocardial infarction and enrolled in the American Heart Association’s Get With the Guidelines Coronary Artery Disease registry [...]

Pre-Hospital Electrocardiography by Emergency Medical Personnel Effects on Scene and Transport Times for Chest Pain and ST-Segment Elevation Myocardial Infarction Patients

Objectives

This study sought to measure the impact of pre-hospital (PH) electrocardiography (ECG) on scene-to-hospital time for patients with chest pain of cardiac origin and those with ST-segment elevation myocardial infarction (STEMI). Background

Pre-hospital ECG decreases door-to balloon (D2B) time for STEMI patients. However,obtaining a PH ECG might prolong scene time. We investigated [...]

Prognostic Utility of Neutrophil Gelatinase-Associated Lipocalin in Predicting Mortality and Cardiovascular Events in Patients With ST-Segment Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention

Objectives

The aim of this study was to investigate the prognostic role of neutrophil gelatinase–associated lipocalin (NGAL) in a large population of patients with ST-segment elevation myocardial infarction. Background

NGAL is a glycoprotein released by damaged renal tubular cells and is a sensitive maker of both clinical and subclinical acute kidney injury. New data [...]

Echocardiographic Findings During Stress-Induced ST-Segment Elevation in Lead aVR in Ostial Left Main,Left Anterior Descending Stenosis

Journal of the American College of Cardiology current issue

First Results of the DEB-AMI (Drug Eluting Balloon in Acute ST-Segment Elevation Myocardial Infarction) Trial:A Multicenter Randomized Comparison of Drug-Eluting Balloon Plus Bare-Metal Stent Versus Bare-Metal Stent Versus Drug-Eluting Stent in Primary Percutaneous Coronary Intervention With 6-Month Angiographic,Intravascular,Functional,and Clinical Outcomes

Objectives

The goal of this study was to compare angiographic,intravascular imaging,and functional parameters,as well as the clinical outcomes of patients treated with drug-eluting balloon (DEB) plus bare-metal stent (BMS) versus BMS versus drug-eluting stent (DES) for ST-segment elevated acute myocardial infarction (STEMI).

Background

Concerns remain regarding the long-term safety of DES [...]