Coronary computed tomography angiography (CTA) has emerged as a noninvasive method for direct visualization of coronary artery disease,with previous studies demonstrating high diagnostic performance of CTA compared with invasive coronary angiography. However,CTA assessment of coronary stenoses tends toward overestimation,and even among CTA-identified severe stenosis confirmed at the time of invasive coronary angiography,[...]
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Bertalan Mesko,MD,PhD    Alzheimer's Disease Education & Referral Center  Colorectal Cancer Screen  CDC.gov  
 | Objectives This study investigated whether the technitium-99m sestamibi (MIBI) washout rate (WR) would predict mitochondrial damage and myocardial dysfunction in patients with dilated cardiomyopathy (DCM). Background Myocardial mitochondrial damage reduces adenosine triphosphate production,resulting in myocardial dysfunction. Increased myocardial 99mTc-MIBI washout is reportedly caused by mitochondrial dysfunction. Methods Twenty DCM patients (New York Heart [...] A dermatology researcher at Case Western Reserve University School of Medicine has secured a five-year,$ 1.9 million federal grant to explore whether a specific molecule may play a pivotal role in the development and progression of psoriasis. Newswise:MedNews Objectives FIRST (Fractional Flow Reserve and Intravascular Ultrasound Relationship Study) aimed to determine the optimal minimum lumen area (MLA) by intravascular ultrasound (IVUS) that correlates with fractional flow reserve (FFR) and to assess the correlation between virtual histology IVUS and FFR for intermediate coronary lesions. Background FFR is considered the gold standard for assessing [...] Objectives The goal of this study was to determine the diagnostic accuracy of dynamic 3-dimensional (3D) whole heart myocardial perfusion cardiovascular magnetic resonance (CMR) against invasively determined fractional flow reserve (FFR) and to establish the correlation between myocardium at risk defined by using the invasive Duke Jeopardy Score (DJS) and noninvasive 3D whole heart [...] Sudipta Chattopadhyay,Mohammed F. Alamgir,Nikolay P. Nikitin,Alan S. Rigby,Andrew L. Clark,John G.F. ClelandJan 1,2010;3:35-43 Circ Heart Fail:Most-Cited Full-Text Articles |
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University of Washington - Seattle,WA --------------------------------------  --------------------------------------  University of Washington - Harborview Medical CenterSeattle,WA   Office on Women's Health U.S. Department of Health and Human Services      "Watch your weight & your waist!"     CDC:Public Health
  
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