Protein | Knowledge of Medicine

Response to Lack of Specificity of Commercial Antibodies Leads to Misidentification of Angiotensin Type-1 Receptor Protein [Letter to the Editor]

Hypertension On-line First

Z Pro High Protein Supplement:Recall –Undeclared Soy And Milk

People who have an allergy or severe sensitivity to soy or milk run the risk of a serious or life-threatening allergic reaction if they consume these products. MedWatch Safety Alert RSS Feed

Lack of Specificity of Commercial Antibodies Leads to Misidentification of Angiotensin Type-1 Receptor Protein [Letter to the Editor]

Hypertension On-line First

Protein Family Linked to Autism Suppresses the Development of Inhibitory Synapses

Synapse development is promoted by a variety of cell adhesion molecules that connect neurons and organize synaptic proteins. Many of these adhesion molecules are linked to neurodevelopmental disorders;mutations in neuroligin and neurexin proteins,for example,are associated with autism and schizophrenia. According to a study in The Journal of Cell Biology,another family of [...]

Differential Modulation of Uncoupling Protein 2 in Kidneys of Stroke-Prone Spontaneously Hypertensive Rats Under High-Salt/Low-Potassium Diet [Original Article]

The stroke-prone spontaneously hypertensive rat (SHRsp) represents an animal model of increased susceptibility to high-salt diet–induced cerebral and renal vascular injuries. High blood pressure and genetic factors are viewed as major contributing factors. In high-salt–loaded SHRsp and stroke-resistant SHR animals,we determined blood pressure levels,degree of kidney lesions,renal uncoupling protein 2 (UCP2) gene [...]

Novel Regulation of Cardiac Metabolism and Homeostasis by the Adrenomedullin-Receptor Activity-Modifying Protein 2 System [Original Article]

Adrenomedullin (AM) was identified as a vasodilating and hypotensive peptide mainly produced by the cardiovascular system. The AM receptor calcitonin receptor-like receptor associates with receptor activity-modifying protein (RAMP),one of the subtypes of regulatory proteins. Among knockout mice (–/–) of RAMPs,only RAMP2–/–is embryonically lethal with cardiovascular abnormalities that are the same as AM–/–. [...]

Central Rho Kinase Inhibition Restores Baroreflex Sensitivity and Angiotensin II Type 1 Receptor Protein Imbalance in Conscious Rabbits With Chronic Heart Failure [Original Article]

The small GTPase RhoA and its associated kinase ROCKII are involved in vascular smooth muscle cell contraction and endothelial NO synthase mRNA destabilization. Overactivation of the RhoA/ROCKII pathway is implicated in several pathologies,including chronic heart failure (CHF),and may contribute to the enhanced sympathetic outflow seen in CHF as a result of decreased NO [...]

Merlin protein found to control liver stem cells,prevent tumor development

A protein known to be involved in a rare hereditary cancer syndrome may have a role in the regulation of liver stem cells and the development of liver cancer. Mass General News Releases

Lab Notes:Memory Protein Promising

(MedPage Today) —It may be possible to treat Alzheimer’s disease with a simple protein that thwarts inflammation. Also this week,fixing RNA defects with tiny molecules and signs of hope for blindness. MedPageToday.com –medical news plus CME for physicians

Protein kinase C,an elusive therapeutic target?

Nature Reviews Drug Discovery 11,937 (2012). doi:10.1038/nrd3871

Authors:Daria Mochly-Rosen,Kanad Das &Kevin V. Grimes

Protein kinase C (PKC) has been a tantalizing target for drug discovery ever since it was first identified as the receptor for the tumour promoter phorbol ester in 1982. Although initial therapeutic efforts focused on cancer,additional [...]

CDC Vital Signs™–Learn about the latest public health data. Read CDC Vital Signs™…

CDC:Public Health

May 2013 May 1,2013
A Bang to the Brain:What We Know About Concussions...On Sound Footing:The Health of Your Feet... Ex-Smokers Gain Health Benefits Despite Added Pounds...Allergies and Complementary Medicine,Featured Web Site:NIH BRAIN Initiative […]
April 2013 April 1,2013
The Benefits of Slumber:Why You Need a Good Night’s Sleep...Sleep On It:How Snoozing Strengthens Memories...Brain Scans Give Clues to Antidepressant’s Effects...Living with Low Vision,Featured Web Site:Inside Life Science […]
March 2013 March 1,2013
Keep Your Kidneys Healthy:Catch Kidney Disease Early...Soothing a Sore Throat:What To Do When Your Throat Hurts...Many Doctors Don’t Ask Teens About Alcohol...Listen to Health Information from NIH,Featured Web Site:Herbs at a Glance […]
February 2013 February 1,2013
Shape Your Family’s Habits:Helping Kids Make Healthy Choices...Chew on This:Healthy Teeth for Baby and Beyond...Therapy Shows Promise for Peanut Allergy...Relaxation Techniques for Stress?,Featured Web Site:Check Up on Your Bones […]

NIH study finds leisure-time physical activity extends life expectancy as much as 4.5 years December 28,2012
Leisure-time physical activity is linked to longer life expectancy,even at low levels of activity regardless of one’s body weight. Transcript […]
Inhaled corticosteroid for childhood asthma may affect adult height December 13,2012
An NIH-funded study has found potential small effect on growth rate among those who use inhaled corticosteroids for asthma. Transcript […]
Food insufficiency linked to frailty December 11,2012
An NIH-funded study shows a link between being frail and food insufficiency. Transcript […]
The science behind cancer screening December 5,2012
Screening can help doctors find and treat some types of cancer early. Transcript […]

Infection Makes Mosquitoes Immune to Malaria Parasites May 20,2013
Researchers established a bacterial infection in mosquitoes that helps fight the parasites that cause malaria. These infected insects could be a significant tool for malaria control. […]
3-D Printing of Working Bionic Ears May 20,2013
Researchers used 3-D printing to create functional bionic ears that receive radio signals. Using similar techniques,it may one day be possible to create bionic implants and prostheses. […]
Clues to Congenital Heart Disease May 20,2013
A large-scale genomic analysis found that non-inherited mutations in hundreds of genes together account for about 1 in 10 cases of severe congenital heart defects,the most common type of birth defect. […]
Hormone May Help Treat Diabetes May 13,2013
A hormone called betatrophin prompts cells in the pancreas to multiply and produce more insulin. The finding,in mice,may lead to new ways to combat diabetes. […]

eHealth Topics

Response to Lack of Specificity of Commercial Antibodies Leads to Misidentification of Angiotensin Type-1 Receptor Protein [Letter to the Editor]

Z Pro High Protein Supplement:Recall –Undeclared Soy And Milk

Lack of Specificity of Commercial Antibodies Leads to Misidentification of Angiotensin Type-1 Receptor Protein [Letter to the Editor]

Protein Family Linked to Autism Suppresses the Development of Inhibitory Synapses

Differential Modulation of Uncoupling Protein 2 in Kidneys of Stroke-Prone Spontaneously Hypertensive Rats Under High-Salt/Low-Potassium Diet [Original Article]

Novel Regulation of Cardiac Metabolism and Homeostasis by the Adrenomedullin-Receptor Activity-Modifying Protein 2 System [Original Article]

Central Rho Kinase Inhibition Restores Baroreflex Sensitivity and Angiotensin II Type 1 Receptor Protein Imbalance in Conscious Rabbits With Chronic Heart Failure [Original Article]

Merlin protein found to control liver stem cells,prevent tumor development

Lab Notes:Memory Protein Promising

Protein kinase C,an elusive therapeutic target?

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