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Surgery for Common Woman’s Condition May Not be Effective over Long-Term

The initial success rates of the most durable surgery for pelvic organ prolapse,a common condition in women,declines over the long-term,according to data published in the Journal of the American Medical Association. Newswise:MedNews

Sjögren’s syndrome has high long-term complication rate

BIRMINGHAM,ENGLAND – Patients with Sjögren’s syndrome had a diverse and high rate of long-term complications over the course of a 25-year review of cases seen at a single center.

Between 1986 and…

Rheumatology News

Long-term Control of Arterial Hypertension and Regression of Left Ventricular Hypertrophy With Treatment of Primary Aldosteronism [Original Article]

Primary aldosteronism (PA),a common cause of high blood pressure (BP),induces left ventricular (LV) hypertrophy and an excess rate of cardiovascular events. Whether its treatment provides long-term cure of hypertension and regression of cardiovascular damage remains uncertain. To the aim of assessing the effect of treatment of PA on BP and LV changes,we [...]

Faecal Incontinence:Collagen injection:a long-term treatment for faecal incontinence?

Nature Reviews Gastroenterology &Hepatology 10,196 (2013). doi:10.1038/nrgastro.2013.44

Findings from a retrospective study have demonstrated the long-term clinical effectiveness of collagen injection into the internal anal sphincter for the treatment of passive faecal incontinence. Of the 100 patients in the study,56 patients had an improvement in faecal incontinence score and 68 patients [...]

No Easy Answers for Long-Term Care

Tax time has just passed. For many people,that’s a time to take stock of finances and to start planning for the future. That should include plans in case you or a family member needs long-term care. It’s a tough topic. But if you plan ahead,you’re more likely to get the kind of care [...]

A Scientist on a Mission:Not Enough Is Being Done to Educate Those Living in Border Communities About the Long-Term Effects of Antibiotic Overuse and Misuse,South Texas Scientist Says

When thousands of researchers gather in Boston for the Experimental Biology 2013 conference this weekend,many of them undoubtedly will be presenting work related to the hunt for the next generation of antibiotics and how to battle back existing and emerging superbugs. But for one scientist from Texas Rio Grande Valley,it’s not about what [...]

Renal Responses to Long-Term Carotid Baroreflex Activation Therapy in Patients With Drug-Resistant Hypertension [Original Article]

Carotid baroreflex activation has been demonstrated to provide enduring reductions in arterial blood pressure. The aim of this study was to investigate the effect of long-term therapy on renal function. A total of 322 patients were enrolled in the Rheos Pivotal Trial. Group 1 consisted of 236 patients who started baroreflex activation therapy 1 month [...]

Long-term anabolic steroid use may weaken heart more than previously thought

Long-term anabolic steroid use may weaken the heart more than previously thought and may increase the risk of heart failure,according to a study led by MGH investigator Aaron Baggish,MD. Mass General News Releases

Favorable long-term outcomes in patients with histologically dysplastic nevi that approach a specimen border

Background:Patients with multiple clinically dysplastic nevi are at increased risk for development of melanoma. However,the risk of melanoma arising in a histologically dysplastic nevus (HDN) is unknown.Objective:We sought to determine the rate of melanoma development in patients with HDNs that approached a microscopic border but were not re-excised.Methods:We performed a retrospective [...]

Concentrations of Insulin Glargine and Its Metabolites During Long-Term Insulin Therapy in Type 2 Diabetic Patients and Comparison of Effects of Insulin Glargine,Its Metabolites,IGF-I,and Human Insulin on Insulin and IGF-I Receptor Signaling

We investigated:1) the ability of purified glargine (GLA),metabolites 1 (M1) and 2 (M2),IGF-I,and NPH insulin to activate the insulin receptor (IR)-A and IR-B and IGF-I receptor (IGF-IR) in vitro;2) plasma concentrations of GLA,M1,and M2 during long-term insulin therapy in type 2 diabetic patients;and 3) IR-A and IR-B [...]