Scientists have discovered that fat cells in the knee secrete a protein linked to arthritis,a finding that paves the way for new gene therapies that could offer relief and mobility to millions worldwide. ar “We found that fat in the knee joints secretes a protein called pro-factor D which gives rise to another protein [...]
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Bertalan Mesko,MD,PhD    Alzheimer's Disease Education & Referral Center  Colorectal Cancer Screen  CDC.gov  
 | Nature Reviews Drug Discovery 12,371 (2013). doi:10.1038/nrd3975 Author:Kim Lewis The spread of resistant bacteria,leading to untreatable infections,is a major public health threat but the pace of antibiotic discovery to combat these pathogens has slowed down. Most antibiotics were originally isolated by screening soil-derived actinomycetes during the golden era of antibiotic [...] Title:Gene Discovery May Offer Breakthrough for Rare LeukemiaCategory:Health NewsCreated:5/9/2013 12:35:00 PMLast Editorial Review:5/10/2013 12:00:00 AM MedicineNet Daily News Researchers have discovered that a particular type of protein (hormone) found in fat cells helps regulate how glucose (blood sugar) is controlled and metabolized in the liver. Using experimental models and state-of-the-art technology,the scientists found that switching off this protein leads to better control of glucose production from the liver,revealing a potential new [...] A series of biomarker discoveries developed by Robert B. Jenkins M.D.,Ph.D.,George Klee,M.D.,Ph.D.,George Vasmatzis,Ph.D.,and their colleagues at Mayo Clinic,along with Donald Connelly,M.D.,Ph.D.,of the University of Minnesota,have resulted in a licensed technology that will benefit prostate cancer patients globally. Mayo Clinic Research News and Discovery’s [...] J. Levinson et al. Emerging Infectious Diseases Journal Researchers have made a discovery in neuroscience that could offer a long-lasting solution to eating disorders such as obesity. It was previously thought that the nerve cells in the brain associated with appetite regulation were generated entirely during an embryo’s development in the womb and therefore their numbers were fixed for life. But new research [...] For her work in uncovering the genetic link between two different but related forms of neurodegenerative disease,Rosa Rademakers,Ph.D.,a neurogeneticist at Mayo Clinic in Florida,will receive the 2013 Sheila Essey Award today during the annual meeting of the American Academy of Neurology (AAN). Mayo Clinic Research News and Discovery’s Edge [...] Nature Reviews Drug Discovery 12,205 (2013). doi:10.1038/nrd3954 Authors:Terry Kenakin &Arthur Christopoulos Agonists of seven-transmembrane receptors,also known as G protein-coupled receptors (GPCRs),do not uniformly activate all cellular signalling pathways linked to a given seven-transmembrane receptor (a phenomenon termed ligand or agonist bias);this discovery has changed how high-throughput screens are [...] University of Michigan research sheds new light on why certain people are more likely to suffer from rheumatoid arthritis –paving the way to explore new treatments for both arthritis and other autoimmune diseases…Arthritis / Rheumatology News From Medical News Today |
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University of Washington - Seattle,WA --------------------------------------  --------------------------------------  University of Washington - Harborview Medical CenterSeattle,WA   Office on Women's Health U.S. Department of Health and Human Services      "Watch your weight & your waist!"     CDC:Public Health
  
 U.S. Department of Health & Human ServicesNational Health Information Center
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