Gene therapy:Crossing mitochondrial barriers
Nature Reviews Drug Discovery 11,439 (2012).
doi:10.1038/nrd3762
Author:Alexandra Flemming
A large number of diseases (as well as ageing) are associated with mitochondrial dysfunction,and over 200 pathogenic mitochondrial DNA mutations have so far been identified. There is no treatment for these diseases,and many of them are fatal. Gene therapy could be an attractive
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