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Penn Researcher Named 2013 Pew Scholar in the Biomedical Sciences

Claudio Giraudo,PhD,assistant professor of Pathology and Laboratory Medicine,Perelman School of Medicine,University of Pennsylvania and The Children’s Hospital of Philadelphia was named as a 2013 Pew Scholar in the Biomedical Sciences.

Penn Medicine News

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Enrolling Clinical Trials:Adoptive Immunotherapy for Chemotherapy Resistant or Refractory CD-19+ Leukemia and Lymphoma

Researchers at Penn have initiated a clinical trial to evaluate the efficacy and safety of CTL-019 (formerly CART-19) for adoptive immunotherapy in patients with relapsed or chemotherapy-refractory chronic lymphocytic leukemias (CLL) and acute lymphoblastic leukemias (ALL) clinicaltrials.gov identifier:NCT01029366. In the near future this trial will be open to patients with relapsed or refractory CD19+ [...]

Enrolling Clinical Trials:Intrapleural Adenoviral-Mediated Interferon-Alpha Gene Transfer for Malignant Pleural Mesothelioma

Pulmonary,Allergy and Critical Care Division • Abramson Cancer Center • Mesothelioma and Pleural Program  Researchers at the Perelman School of Medicine are conducting a clinical trial to evaluate a promising new gene therapy approach to malignant pleural mesothelioma (MPM). A cancer of the mesothelial lining of the pleura,peritoneum and pericardium,mesothelioma is [...]

Penn Medicine’s Peter Reese,MD,Named a Greenwall Faculty Scholar

The Greenwall Foundation has named Penn Medicine’s Peter Reese,MD,MSCE,a leading voice for improving organ donor rates and access to transplant,as a 2013 Greenwall Faculty Scholar in Bioethics.

Penn Medicine News

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Free Skin Cancer Prevention and Melanoma Conferences

CANPrevent Skin Cancer

Penn’s Abramson Cancer Center invites you and your loved ones to attend CANPrevent Skin Cancer,a free educational conference for anyone interested in learning about preventing skin cancer.

CANPrevent Skin Cancer is designed to address the personal and medical issues facing those at risk for skin cancer. The conference provides patient-focused information [...]

Penn Neuroscientist Receives Outstanding Scientific Achievement Award from Sleep Research Society

Amita Sehgal,PhD,the John Herr Musser Professor of Neuroscience and a Howard Hughes Medical Institute investigator,at the Perelman School of Medicine at the University of Pennsylvania,was given the Outstanding Scientific Achievement Award for 2013 at the Association of Professional Sleep Societies meeting in Baltimore.

Penn Medicine News

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Enrolling Clinical Trials:Autologous Whole Tumor Vaccines For Recurrent Ovarian Cancer

• Department of Obstetrics and Gynecology • Abramson Cancer Center • Ovarian Cancer Research Center

Researchers at the Penn Ovarian Cancer Research Center (OCRC) are conducting clinical trials to examine the efficacy and safety of personalized tumor vaccines for the treatment of recurrent ovarian,fallopian tube,primary peritoneal and papillary serous endometrial cancers.

Cancer [...]

EMT and Dissemination Precede Pancreatic Tumor Formation

From the Spring 2013 Penn Medicine Gastroenterology Division Newsletter

Currently,two major paradigms have been proposed to explain the metastatic process. The first,or classical model,sees metastasis as the final step in a progressive sequence in which tumors acquire mutations that promote invasive behavior and dissemination late in tumor evolution. The alternative [...]

Penn Study Shows How Immune System Peacefully Co-exists with “Good”Bacteria

The human gut is loaded with commensal bacteria – “good”microbes that,among other functions,help the body digest food. The gastrointestinal tract contains literally trillions of such cells,and yet the immune system seemingly turns a blind eye. However,in several chronic human diseases such as inflammatory bowel disease (IBD),HIV/AIDS,cancer,cardiovascular disease,[...]

Pancreatitis Research

The Rustgi lab is investigating the ways in which pancreatic development and regeneration and pancreatitis and cancer overlap. Funded by the NIH,the group pioneered the use of 3-dimensional cell culture model systems,and uses these with animal models and human tissues to identify key genes and pathways that drive these processes. A recent [...]