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Arterial Stiffness From Monitoring of Timing of Korotkoff Sounds Predicts the Occurrence of Cardiovascular Events Independently of Left Ventricular Mass in Hypertensive Patients [Original Article]

Several studies have established that the increase in arterial stiffness (AS) is a cardiovascular risk factor but to date no studies have evaluated in hypertensive patients its prognostic value in comparison with another powerful risk factor,left ventricular mass (LVM) as measured by echocardiography. We prospectively evaluated the prognostic value of AS and LVM in [...]

Impact of Baseline Heart Failure Burden on Post-Implantable Cardioverter-Defibrillator Mortality Among Medicare Beneficiaries

Objectives

This study sought to assess the impact of baseline heart failure (HF) burden on survival with primary implantable cardioverter-defibrillator (ICD) among Medicare recipients. Background

Survival after primary ICD implantation may differ between trial and Medicare populations. Methods

Linking data from the CMS (Centers for Medicare and Medicaid Services) ICD registry and the Medicare [...]

Rotational Vertebral Artery Occlusion:Mechanisms and Long-term Outcome [Original Contribution]

Background and Purpose—

To elucidate the mechanisms and prognosis of rotational vertebral artery occlusion (RVAO).

Methods—

We analyzed clinical and radiological characteristics,patterns of induced nystagmus,and outcome in 21 patients (13 men,aged 29–77 years) with RVAO documented by dynamic cerebral angiography during an 8-year period at 3 University Hospitals in Korea. The follow-up [...]

Treatment of Left Ventricular Assist Device Thrombosis With Extended Catheter-Directed Intraventricular Thrombolytic Therapy [Images and Case Reports in Heart Failure]

Circulation:Heart Failure recent issues

Truly Refractory Hypertension [Hypertension Grand Rounds]

Hypertension On-line First

Platelet Function Tests in Clinical Cardiology Unfulfilled Expectations

This review is a critical evaluation of publications in the past decade on the usefulness of platelet function tests (PFTs) in clinical cardiology,in aiding diagnosis,predicting risk,and monitoring therapy. The ideal PFT should:1) detect baseline platelet hyperreactivity;2) allow individualization of antiplatelet medication;3) predict thrombotic risk;and 4) predict bleeding risk. [...]

Inside This Issue

Journal of the American College of Cardiology Current Issue

Arterial Stiffness as an Imaging Biomarker:Are All Pathways Equal? [Editorial Commentary]

Hypertension On-line First

Framingham Stroke Risk Score and Cognitive Impairment for Predicting First-Time Stroke in the Oldest Old [Original Contribution]

Background and Purpose—

Predictive value of the conventional risk factors for stroke attenuates with age. Cognitive impairment has been implicated as a potential predictor for stroke in older subjects. Our aim was to compare the Framingham stroke risk score with cognitive functioning for predicting first-time stroke in a cohort of the oldest old individuals.

Methods—[...]

Evaluation of Ranolazine in Patients With Type 2 Diabetes Mellitus and Chronic Stable Angina Results From the TERISA Randomized Clinical Trial (Type 2 Diabetes Evaluation of Ranolazine in Subjects With Chronic Stable Angina)

Objectives

This study sought to examine the efficacy of ranolazine versus placebo on weekly angina frequency and sublingual nitroglycerin use in subjects with type 2 diabetes mellitus,coronary artery disease (CAD),and chronic stable angina who remain symptomatic despite treatment with up to 2 antianginal agents. Background

Patients with diabetes have more extensive CAD [...]